Zurich and New York, October 30, 2025 - (JCN Newswire via SeaPRwire.com) - Hitachi Energy, a wholly owned subsidiary of Hitachi, Ltd., today announced a strategic partnership with Blackstone Energy Transition Partners (“Blackstone”) to expand and strengthen its Service business, supporting customers in maintaining the reliability and safety of power infrastructure across North America. As part of the partnership, Hitachi Energy will acquire a stake in Shermco – a leading provider of comprehensive maintenance, repair, testing, commissioning, and design services in North America, recently acquired by private equity funds affiliated with Blackstone.The partnership brings together three industry leaders: Hitachi Energy, a global technology leader in electrification; Blackstone, the world’s largest alternative asset manager; and Shermco, a leading provider of electrical services in the U.S. and Canada. Together, they will seek to expand service capacity and capabilities to deliver comprehensive lifecycle support for critical energy infrastructure, from power generation and transmission to data centers and industrial electrification.“Investing in Shermco in partnership with Blackstone enables Hitachi Energy to accelerate our growth and expand service capabilities across North America. Our investment strengthens our service offering as we continue to scale, helping customers maintain and extend the life of existing assets while making the grid stronger, more resilient and fit for the future.”“We’re thrilled to welcome Hitachi Energy as a strategic partner alongside Blackstone,” said Phil Petrocelli, CEO of Shermco. “This investment is a testament to our commitment to serving our customers’ essential power needs and reputation for safety and excellence. With this additional support and resources, we look forward to expanding our footprint and capabilities to continue to accelerate our growth together.”“Hitachi Energy is a global leader across technology and energy with deep digital and operational expertise,” said David Foley, Global Head of Blackstone Energy Transition Partners. “We are excited to partner with Hitachi Energy to build on Shermco's success alongside Phil Petrocelli and its exceptional management team.” JP Munfa and Darius Sepassi, Senior Managing Directors at Blackstone, added, “Hitachi Energy’s investment in Shermco brings together a global technology leader in electrification with one of the leading North American providers of mission-critical maintenance, testing and design services for electrical equipment. We are thrilled to be partnering with Hitachi Energy and look forward to working together to accelerate Shermco’s next phase of growth in an era of rapid electrification and increasing demand.”Hitachi Energy’s $1 billion global investment in ServiceIn addition, Hitachi Energy is investing more than $1 billion USD globally to expand its Service footprint, launching new digital service solutions with HMAX Energy, and growing its workforce — including the development and certification of over 5,000 additional service experts worldwide. “By combining Hitachi Energy’s grid expertise and digital solutions with Shermco’s nationwide field service presence, we will set a new benchmark for electrical infrastructure services – creating the leading service partner in North America driving asset reliability and performance as well as digital innovation for utilities, industries and data centers alike,” said Wolf Mueller, Managing Director of Hitachi Energy’s Service Business.Strengthening Service capabilities for the electricity eraGlobally, power grids are aging, and the experienced workforce is retiring, creating significant challenges. As electrification accelerates across industries, transportation, and digital infrastructure, service is the backbone of grid modernization. Much of today’s grid infrastructure – more than 70 percent of U.S. transmission lines1 – is decades old, nearing or past its intended lifecycle, leading to higher outage risks, cyber vulnerabilities and costly emergency repairs. Service is critical to help data centers, utilities and industries maintain, upgrade, and optimize their infrastructure and increase the reliability, safety, flexibility and sustainability of energy systems.1DOE, What does it take to modernize the U.S.electric grid?(1) Founded in 1974 and headquartered in Texas, Shermco is one of the largest electrical testing organizations accredited by the InterNational Electrical Testing Association (“NETA”), providing comprehensive electrical system maintenance, repair, testing, commissioning and design services, with more than 600 NETA technicians and 200 engineers across 40 service centers in the U.S. and Canada. Shermco provides critical services for data centers, utilities and diversified commercial and industrial end-markets, partnering with customers to enhance the safety, reliability and efficiency of their critical electrical infrastructure, while minimizing downtime and outages.(2) HMAX Energy is Hitachi’s upcoming digitally enabled and AI-powered services offering related to the energy sector. As a key pillar of the company’s Lumada 3.0 strategy, HMAX Energy integrates digital capabilities, domain expertise, service excellence, and installed base intelligence to maximize uptime, safety, efficiency, and asset lifetime. These capabilities will empower customers to shift from reacting to predicting - future-proofing their energy infrastructure.About Hitachi, Ltd.Through its Social Innovation Business (SIB) that brings together IT, OT (Operational Technology) and products, Hitachi contributes to a harmonized society where the environment, wellbeing, and economic growth are in balance. Hitachi operates globally in four sectors – Digital Systems & Services, Energy, Mobility, and Connective Industries – and the Strategic SIB Business Unit for new growth businesses. With Lumada at its core, Hitachi generates value from integrating data, technology and domain knowledge to solve customer and social challenges. Revenues for FY2024 (ended March 31, 2025) totaled 9,783.3 billion yen, with 618 consolidated subsidiaries and approximately 280,000 employees worldwide. Visit us at https://www.hitachi.com.About Hitachi EnergyHitachi Energy is a global technology leader in electrification, powering a sustainable energy future with innovative power grid technologies with digital at the core. Over three billion people depend on our technologies to power their daily lives. With over a century in pioneering mission-critical technologies like high-voltage, transformers, automation, and power electronics, we are addressing the most urgent energy challenge of our time – balancing soaring electricity demand, while decarbonizing the power system. With an unparalleled installed base in over 140 countries, we co-create and build long-term partnerships across the utility, industry, transportation, data centers, and infrastructure sectors. Headquartered in Switzerland, we employ over 50,000 people in 60 countries and generate revenues of around $16 billion USD.https://www.hitachienergy.comhttps://www.linkedin.com/company/hitachienergyhttps://x.com/HitachiEnergyAbout Blackstone Energy Transition PartnersBlackstone Energy Transition Partners is Blackstone’s strategy for control-oriented equity investments in energy-related businesses, a leading energy investor with a successful long-term record, having committed over $27 billion of equity globally across a broad range of sectors within the energy industry. Our investment philosophy is based on backing exceptional management teams with flexible capital to provide solutions that help energy companies grow and improve performance, thereby delivering more reliable, affordable and cleaner energy to meet the needs of the global community. In the process, we build stronger, larger scale enterprises, create jobs and generate lasting value for our investors, employees and all stakeholders. Further information is available at https://www.blackstone.com/our-businesses/blackstone-energy-transition-partners/.About ShermcoHeadquartered in Irving, TX, Shermco provides electrical testing, maintenance, commissioning and repair services to a wide range of utility, industrial, energy and other end markets. With more than 40 locations, Shermco serves a diversified blue-chip client base across North America. The Company is an active participant in NETA (the InterNational Electrical Testing Association), EASA (Electrical Apparatus Service Association), and ACP (American Clean Power Association). For more information, visit www.shermco.com.  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Vehicle transport robotsTOKYO, October 30, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries Machinery Systems (MHI-MS), a part of Mitsubishi Heavy Industries (MHI) Group, will conduct demonstration testing of finished vehicle logistics (FVL) using vehicle transport robots to autonomously move automobiles. Following a proposal adopted for "Testbed Support Subsidy Program"(*1) conducted by Okinawa Prefecture, demonstration testing is scheduled to begin on December 1 this year at the prefecture's temporary vehicle storage yard (motor pool) at Nakagusuku Port (Uruma, Okinawa Prefecture).Vehicle transport robots are used to autonomously move finished vehicles at automobile manufacturing plants, motor pools, and for automated valet parking at shopping malls, theme parks, and airports.(*2) The system enables automated transport even if the vehicle itself is not equipped with autonomous driving capabilities or communication functions, and can be widely utilized in motor pools for both new and used cars without the need for vehicle modification or extensive installation of equipment on the infrastructure side, and without major changes to current operations.MHI-MS has been jointly developing the first advanced automated transport robot business in Japan with Stanley Robotics, a French venture company, since 2021. As of October 2025, seven core patents have been registered in Japan for automated transport robots, which will drive market expansion. In consideration of the unique conditions in Japan, domestic development of a customizable system was completed in March this year.Okinawa, the site of the demonstration testing for finished vehicle transport, is a region with a high rate of private car ownership, with the number of private cars owned per capita of the population over the age of 20 exceeding the national average. Used cars especially are preferred by many prefectural residents because they are less expensive than new cars, and play an important role in the infrastructure supporting everyday life. In addition, because of the many tourist arrivals in Okinawa from Japan and abroad, the number of rental car registrations is one of the highest in Japan. Registered rental cars are replaced every few years and sold on the market as used cars. In this way, the used car market supports Okinawa's industry and the everyday lives of people.The Nakagusuku Port Motor Pool is mainly used for temporary storage of used cars prior to shipping, and transport services such as the loading and unloading of used cars are conducted at the site on a regular basis. In addition, the outdoor work environment has become harsher due to global warming, so reducing the physical burden on workers and ensuring a sustainable working style is an urgent matter. Strategies to address labor shortages due to the declining birth rate and aging population have also become a concern. In addition, the application of DX (digital transformation) technologies for vehicle management, such as visualization of the storage location of used cars, was also a factor for future consideration.MHI-MS decided to participate in this program in Okinawa Prefecture to demonstrate the effectiveness of vehicle transport robots as a solution to such challenges. The demonstration testing will evaluate the potential for improving the working environment, and responding to labor shortages, as well as "human-centered robot utilization" such as robot-based yard management systems and DX to handle vehicle location information. The tests will also evaluate the potential contribution to decarbonization efforts by confirming supplemental benefits such as curbing CO2 emissions through reduced driving of gasoline-powered vehicles.Going forward, as a company committed to creating new value for society and solving future societal issues through mechatronics, MHI-MS will establish a new future for finished vehicle transport that is friendly to both people and the planet.(*1) "Testbed Support Subsidy Program (Okinawa Prefecture Subsidy Program)" provides support for proof-of-concept experiments within Okinawa Prefecture by companies with innovative digital technologies and services, with the aim of furthering innovation and solutions to societal issues. See the following website for more information about the program. https://testbedislandokinawa.com (Japanese)(*2) When the driver stops at a designated berth close to the facility, the vehicle transport robot moves the vehicle to a vacant space, taking over parking on behalf of the driver. The process is reversed when retrieving the vehicle, with the robot transporting the vehicle back to the berth at the time specified by the driver in advance using the smartphone app. For drivers, there is no need to find a parking space or park, and no concerns about brushing against the adjacent car when opening the door.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

KARIYA, JAPAN, Oct. 30, 2025 - (JCN Newswire via SeaPRwire.com) - DENSO CORPORATION hosted a press briefing at JAPAN MOBILITY SHOW 2025 held at Tokyo Big Sight on October 30.  Shinnosuke Hayashi, President & CEO, DENSO CORPORATIONFull transcript of the speech------------------------------Good morning, I’m Shinnosuke Hayashi from DENSO.Thank you very much for joining us today.Since its founding, DENSO’s journey has evolved alongside the automobile. By focusing on the environment and safety, we have addressed social challenges and expanded our product domains from starter and alternator systems to powertrain, body, thermal, and safety products—covering a wide range of core vehicle functions.To ensure vehicle performance and reliability, we have also pursued deep technological expertise in each domain, evolving our offerings from components to systems.This breadth and depth of technology are unique strengths of DENSO, supporting both the evolution of automobiles and the future of mobility.Today, the world is steadily moving toward carbon neutrality. In the automotive industry, reducing environmental impact and responding to increasingly diverse powertrains have become key challenges.Leveraging our fuel efficiency and emission reduction technologies, along with our electrification expertise, DENSO continues to tackle these challenges by offering products for engine vehicles, HEVs, PHEVs, battery EVs, and FCEVs.Now, we are pleased to announce the development of a new inverter—the core component of electric vehicles.The key to inverter performance lies in semiconductor and cooling technologies.Through extensive R&D—from circuit design to manufacturing processes—we’ve realized a proprietary 3D structure on SiC(silicon carbide) semiconductor wafers, maximizing power efficiency. Additionally, by applying cooling technologies cultivated through car air conditioning systems, we’ve achieved a flat, double-sided cooling structure for the power card. By optimally integrating these technologies as a system, we have reduced power loss by 70% and downsized the core module by about 30% compared to conventional products.This results in the world’s highest power density, contributing to improved energy efficiency across the vehicle.Meanwhile, in the era of Software-Defined Vehicles (SDVs), vehicle intelligence is accelerating through advanced driver assistance and autonomous driving. System-on-Chip (SoC) semiconductors are gaining attention as high-performance digital components capable of running sophisticated software.Unlike general-purpose SoCs, automotive SoCs must withstand harsh conditions unique to vehicles.For over half a century, DENSO has tackled technical challenges such as heat, noise, and vibration in semiconductor development.Building on this experience, we are developing original SoCs that deliver high performance and reliability tailored to automotive needs.We are also advancing the development of an “Integrated Mobility Computer” that controls multiple domains across the vehicle, leveraging our expertise in ECU development across all areas.This computer will help accelerate the spread of vehicle intelligence, contributing to safer and more comfortable mobility for more users.We aim to launch the Integrated Mobility Computer equipped with our original SoC in 2029.Production is planned at our next-generation factory in Aichi Prefecture (Zenmyo Plant), which will use advanced technologies to operate 24 hours a day.DENSO will extend its efforts toward the environment and safety beyond the evolution of automobiles to encompass the entire mobility society.At this year’s Japan Mobility Show, we are showcasing initiatives that expand these efforts to society —such as energy management across entire cities and safe, comfortable mobility realized through vehicles connected to society.We invite you to visit our exhibits and experience the future of mobility with DENSO.“With refined technology, we open the future.”We have taken on numerous challenges through the power of technology.The driving force behind this is the passion of the people involved in manufacturing.DENSO will continue to unite the passion of our employees, and together with automakers and many partners who share our vision for the future, we will keep taking on new challenges.Thank you very much for your attention.-------------------------Videos and images from the press conference are also available at the link below. https://www.denso.com/global/en/about-us/corporate-info/press-info  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Cranston, RI, USA & Neuchâtel, Switzerland, Oct 29, 2025 - (JCN Newswire via SeaPRwire.com) - Gannon & Scott, a leading provider of precious metal refining and recovery services in North America, today announced that it has signed a definitive agreement to join Metalor Technologies, one of the most respected names in the global precious metals industry and part of TANAKA. The transaction is expected to close following approval by regulatory authorities, after which Gannon & Scott will become a wholly owned subsidiary of Metalor Technologies, enhancing the capabilities of both organizations and positioning them to better serve their worldwide customer base.Founded in 1919, Gannon & Scott has earned a strong reputation for secure, environmentally responsible refining solutions across industries including electronics, aerospace, electroplating, medical devices, and jewelry manufacturing. With facilities in Rhode Island and Arizona, the company is recognized for its proprietary thermal reduction technology and waste minimization processes — innovations that align seamlessly with Metalor Technologies’ global standards for excellence.“We are thrilled to become part of an organization that shares our commitment to innovation, customer success, and sustainable growth,” said Christopher Jones, President of Gannon & Scott. “This partnership allows us to build on our strengths while gaining new resources and opportunities. Together, we are well positioned to deliver even greater results for our customers, employees, and partners.”A Stronger Offering for CustomersAs part of Metalor Technologies, Gannon & Scott customers will benefit from:Expanded refining capabilities across all precious metals (gold, silver, platinum, palladium, rhodium, iridium, ruthenium) through global sourcing and recycling channels.Access to high-purity precious metals, technical products, compounds, and chemicals. Advanced technology and analytical services powered by Metalor Technologies’ international laboratories and R&D network.A global refining infrastructure enabling more agile service to international operations.“Since 1919, Gannon & Scott has consistently grown. Becoming part of Metalor Technologies provides a tremendous opportunity to accelerate that growth,” said Joe Peixoto, CEO of Gannon & Scott. “It opens the door to new capabilities, new markets, and new professional development opportunities for our employees. Our customers can be assured that the high level of service, trust, and security they’ve always relied on will remain unchanged — now strengthened by access to a broader suite of products and services.”Customers can expect a seamless transition. In particular, Gannon & Scott’s leadership team, skilled workforce, facilities, and day-to-day operations will remain unchanged.“The acquisition of Gannon & Scott, the most reputable secondary refiner in the United States, represents a strategic step in strengthening Metalor Technologies’ vertical integration,” said Nicolas Carrera, CEO of Metalor Technologies. “By securing direct access to low-grade materials such as electronic waste, we reinforce our commitment to sustainable sourcing and responsible recycling of precious metals, while expanding our ability to serve customers and partners with greater efficiency and environmental responsibility.”“Joining the forces of Gannon & Scott with our existing refining operations in the United States, which have recently begun refining PGMs, will significantly enhance our ability to serve the American market,” said Dr. Yuxing Shang, President of Metalor Technologies’ Refining Group. “This integration allows us to expand the range of services we can offer to both current and future customers in North America, combining advanced capabilities with the trusted expertise of Gannon & Scott.”“We warmly welcome the collaboration between Gannon & Scott and Metalor,” said Koichiro (Frank) Tanaka, Group CEO of TANAKA. “Their partnership will create new synergies within TANAKA, further strengthening our shared commitment to sustainable and responsible precious metal refining for customers and industries worldwide.”About Gannon & Scott Gannon & Scott provides precious metal refining, thermal processing, and secure materials recovery services to businesses across North America. With operations in Cranston, RI, and Phoenix, AZ, the company serves sectors including electronics, plating, jewelry, aerospace, and certified destruction.About Metalor TechnologiesFounded in 1852, Metalor is a global leader in precious metals refining, advanced materials, and fine chemicals. Headquartered in Switzerland with operations in Europe, Asia, and the Americas, and more than 1,550 employees worldwide, Metalor is recognized for its refining excellence, high-quality products, and long-standing partnerships across banking, luxury goods, electronics, and chemical sectors. The company is part of TANAKA.About TANAKAFounded in 1885 and headquartered in Japan, TANAKA offers a broad range of advanced precious metal materials for industrial use, as well as assets and jewelry. As a global precious metals specialist, TANAKA’s group companies worldwide collaborate in procurement, R&D, manufacturing, sales, customer service, and recycling to deliver comprehensive products and services. The group has 5,591 employees, and its consolidated net sales for fiscal year 2024 totaled 846.9 billion yen (approximately 5.96 billion USD).Press inquiriesTANAKA PRECIOUS METAL GROUP Co., Ltd.https://www.tanaka.co.jp/support/req/other_contact_e/index.htmlPress release: http://www.acnnewswire.com/docs/files/251028.pdf  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Oct 29, 2025 - (JCN Newswire via SeaPRwire.com) - Olympus Corporation (Olympus), a global MedTech company committed to making people’s lives healthier, safer and more fulfilling, today announced the launch of the NBI+TXI™ observation mode, which combines Narrow Band Imaging (NBI™ mode) and Texture and Color Enhancement Imaging (TXI™ mode) into a single view. Sales of the EVIS X1™ endoscopy system featuring the NBI+TXI mode will begin in Japan in November 2025, with launches in other regions to follow pending local regulatory approvals.The latest NBI mode, and the TXI observation mode, combined in the CV-1500.Since its initial launch in April 2020, the EVIS X1 endoscopy system has supported healthcare professionals with advanced imaging technologies including TXI mode, NBI mode and RDI™ mode (Red Dichromatic Imaging). These proprietary innovations have contributed to more precise observation and treatment of gastrointestinal and respiratory diseases, including cancer.The NBI+TXI mode further strengthens the EVIS X1 endoscopy system’s diagnostic capabilities by enhancing the brightness correction and contrast information of NBI mode. This enables clearer visualization in darker areas of the image and sharper definition of vascular and mucosal patterns, which can contribute to improved detection and diagnostic accuracy for lesions, including those associated with cancers.According to 2021 statistics from the Ministry of Health, Labour and Welfare1, colorectal cancer has the highest incidence rate among all types of cancer in Japan, with 154,585 cases, followed by lung cancer (124,531 cases), and stomach cancer (112,881 cases). These cancers also rank among the leading causes of cancer-related deaths, with lung cancer first (75,762 deaths), colorectal cancer second (53,131 deaths), and stomach cancer fourth (38,771 deaths).NBI mode, first introduced globally in 2006, brought a revolutionary change to endoscopic imaging by improving visibility of features that were previously difficult to detect, making the invisible visible. The CV-1500 incorporates the latest NBI mode, achieving improved brightness compared to the original NBI mode. TXI mode, introduced with the CV-1500, further improves the visibility of lesions through its image enhancement technology when used with conventional light observation. The combination of these two technologies in the CV-1500, the NBI+TXI observation mode is expected to further enhance and optimize the contrast information in NBI mode images, supporting more precise endoscopic examinations and treatments.NBI+TXI observation mode is expected to enhance the contrast information in NBI mode imaging.Supporting Better Mucosal VisibilityTXI mode supports better visibility of potential and extant lesions, such as areas of inflammation, flat or depressed lesions, or even tiny precursor lesions, by enhancing texture, brightness and color to define subtle tissue differences more clearly. With its advanced imaging technology, TXI mode has the potential to reinvent white light in endoscopy. By supporting better visibility of potential and extant lesions, TXI mode may contribute to higher detection rates and improve qualitative diagnosis.NBI mode is a powerful and proven optical technology creating strong contrast between vessels and surrounding mucosa that allows for a high-confidence optical diagnosis using specific blue and green wavelengths. NBI mode not only supports earlier detection of lesions but also provides a more detailed, higher-contrasted visualization that can improve qualitative diagnosis.“We know that early detection improves patient care and outcomes.” said Kurt Heine, Senior Vice President and General Manager for Gastroenterology, Olympus. “Olympus is committed to providing the advanced endoscopic imaging physicians need to clearly visualize the GI tract and provide timely diagnoses and treatment. We're excited to expand upon the innovations of our EVIS X1 endoscopy system with this combined imaging mode capability and continue elevating the standard of care."Physicians attending JDDW, scheduled for October 30–November 1, 2025 at the Kobe Convention Center will have the opportunity to see the combined NBI+TXI imaging mode firsthand.1 CANCER INCIDENCE OF JAPAN 2021About OlympusAt Olympus, we are committed to Our Purpose of making people’s lives healthier, safer and more fulfilling. As a global medical technology company, we partner with healthcare professionals to provide innovative solutions and services for early detection, diagnosis and minimally invasive treatment, aiming to improve patient outcomes by elevating the standard of care in targeted disease states. For more than 100 years, Olympus has pursued a goal of contributing to society by producing products designed with the purpose of delivering optimal outcomes for its customers around the world. For more information, visit https://www.olympus-global.com/ and follow our global LinkedIn and X accounts.Media contact:Mail: Global-Public_Relations@olympus.com.Olympus Corp [TYO: 7733] [ADR: OLYMY] [STU: OLY1] [FRA: OLYS] https://www.olympus-global.com    Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO and RAHWAY, NJ, Oct. 29, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai (Headquarters: Tokyo, CEO: Haruo Naito) and Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the United States and Canada) today announced results from that Phase 3 LEAP-012 trial evaluating LENVIMA® (lenvatinib), the orally available multiple receptor tyrosine kinase inhibitor (TKI)discovered by Eisai, plus KEYTRUDA® (pembrolizumab), the anti-PD-1 therapy from Merck & Co.,Inc., Rahway, NJ, USA, in combination with transarterial chemoembolization (TACE) for the treatment of patients with unresectable, non-metastatic hepatocellular carcinoma (HCC).At a pre-specified interim analysis, LENVIMA plus KEYTRUDA in combination with TACE did not achieve statistical significance for overall survival (OS), one of the study’s primary endpoints, compared to TACE alone. The likelihood of reaching the protocol-specified threshold for statistical significance for OS at a future analysis was evaluated by Eisai and Merck & Co.,Inc., Rahway, NJ, USA and considered to be low. On this basis, the study will be closed, and the companies are informing investigators of this decision.The safety profile of the LENVIMA plus KEYTRUDA-based regimen was consistent with that observed in previously reported studies evaluating the combination and in earlier analyses of LEAP-012. Further analysis of the data is ongoing. Eisai and Merck & Co., Inc., Rahway, NJ, USA will work with investigators to share the results with the scientific community.As reported previously, LENVIMA plus KEYTRUDA in combination with TACE met the study’s other primary endpoint of progression-free survival (PFS) and demonstrated a statistically significant and clinically meaningful improvement compared to TACE alone. Data from this first interim analysis, which served as the final analysis for the endpoint of PFS, were presented at the European Society for Medical Oncology (ESMO) Congress 2024 and published in The Lancet. With additional follow-up at subsequent analyses, PFS remained consistent.“Although the progression-free survival results from this study are encouraging, unfortunately, the addition of KEYTRUDA plus LENVIMA to TACE did not show the overall survival benefit we hoped,” said Dr. Gregory Lubiniecki, Vice President, Global Clinical Development, MSD Research Laboratories. “We are grateful to the patients and investigators for their important contributions to this study, and our commitment is unwavering as we pursue new therapeutic options for people living with hepatocellular carcinoma, an aggressive and challenging-to-treat cancer.”“The overall survival findings from LEAP-012, along with the previously reported improvement in progression-free survival, provide important insights for treating unresectable, non-metastatic hepatocellular carcinoma,” said Dr. Corina Dutcus, Senior Vice President, Oncology Global Clinical Development Lead at Eisai. “For years, TACE has been a standard of care for these patients, yet many experience disease progression within twelve months. With LEAP-012, we sought to make a meaningful difference for this patient population. LENVIMA continues to play an important role as a monotherapy treatment option for patients with unresectable HCC, and as a company with a deep heritage in liver cancer research, Eisai remains committed to advancing the science.”In July 2025, LENVIMA plus KEYTRUDA in combination with TACE was approved in China to treat unresectable non-metastatic HCC. The LENVIMA plus KEYTRUDA combination is approved in the U.S., the European Union (EU), Japan and other countries for the treatment of advanced renal cell carcinoma (RCC) and certain types of advanced endometrial carcinoma. Results from the LEAP-012 trial do not affect the current approved indications for the LENVIMA plus KEYTRUDA combination, including the approval of LENVIMA plus KEYTRUDA in combination with TACE in China to treat unresectable non-metastatic HCC.LENVIMA monotherapy is approved for the treatment of patients with unresectable HCC in more than 80 countries and regions, including in the U.S., the EU, China and Japan.KEYTRUDA is approved as a monotherapy for the treatment of patients with HCC secondary to hepatitis B who have received prior systemic therapy other than a PD-1/PD-L1-containing regimen in the U.S. and as a monotherapy for the treatment of patients with HCC who have been previously treated with sorafenib or oxaliplatin-containing chemotherapy in China.For more details, please visit: https://www.eisai.com/news/2025/pdf/enews202576pdf.pdf  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

HIROSHIMA, Japan, October 29, 2025 - (JCN Newswire via SeaPRwire.com) - During the press conference at the Japan Mobility Show 2025(*1) today, Mazda Motor Corporation (Mazda) unveiled two vision models, the MAZDA VISION X-COUPE and the MAZDA VISION X-COMPACT (‘X’ pronounced as ‘cross’ ), both embodying the Company’s theme for this year's exhibition: “The Joy of Driving Fuels a Sustainable Tomorrow” for 2035.The MAZDA VISION X-COUPE is a crossover coupe that embodies the further evolution of ‘KODO-Soul of Motion’ design language. It is powered by a plug-in hybrid system integrating a two-rotor rotary turbo engine with a motor and battery. With a maximum output of 510 PS, the vehicle offers a driving range of 160 km in motor-only mode and up to 800 km when operating in combination with the engine. Furthermore, by combining carbon-neutral fuel derived from microalgae with Mazda’s proprietary CO2 capture technology, “Mazda Mobile Carbon Capture,” the vehicle contributes to reducing atmospheric CO2 the more it is driven.MAZDA VISION X-COUPEThe MAZDA VISION X-COMPACT is a model designed to deepen the bond between people and cars through the fusion of a human sensory digital model and empathetic AI. Acting like a close companion, it is capable of engaging in natural conversation and suggesting destinations, helping expand the driver’s world. This represents Mazda’s vision for the future of smart mobility, where vehicles and people form an emotional connection, much like a friend.MAZDA VISION X-COMPACTFurthermore, the All-New MAZDA CX-5 (European specification) (*2) , is on display to the general public for the first time ever. Featuring a spacious interior, refined KODO design, and enhanced Jinba-ittai (oneness between driver and car) driving dynamics, this model represents the evolution of a best-selling vehicle that has sold over 4.5 million units (*3) across more than 100 countries and regions. Designed with the new electronic platform “MAZDA E/E ARCHITECTURE+”, this latest model aims to offer an evolved driving experience.Masahiro Moro, Representative Director, President and CEO of Mazda, stated: “The phrase, ‘The joy of driving fuels a sustainable tomorrow,’ expresses not only Mazda’s fundamental spirit, but also the core of its future challenges. Under the shared global mission of achieving carbon neutrality, Mazda believes that the joy of driving can be a force for positive change for society and the planet. We remain committed to fulfilling the desire of those who love cars and wish to continue driving forever.”Mazda will continue to evolve the ‘Joy of Driving’ based on the value of ‘Radically Human,’ and will aim to deliver the ‘Joy of Living’ by creating exciting mobility experiences in our customers' daily lives.Overview of the MAZDA VISION X-COUPE and MAZDA VISION X-COMPACTModelMAZDA VISION X-COUPEMAZDA VISION X-COMPACTOverall Length5,050 mm3,825 mmOverall Width1,995 mm1,795 mmOverall Height1,480 mm1,470 mmWheelbase3,080 mm2,515 mm*1 Hosted by the Japan Automobile Manufacturers Association, Inc.Press Day: Wednesday, October 29, 8:00-18:00, and Thursday, October 30, 8:00-13:00.Public Day: starting Friday, October 31 until Sunday, November 9.*2 For the new MAZDA CX-5, please see the news release at the following URL.https://newsroom.mazda.com/en/publicity/release/2025/202507/250710a.html*3 Mazda's best-selling model in its current lineup from 2018 to 2024  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

HIROSHIMA, Japan, October 29, 2025 - (JCN Newswire via SeaPRwire.com) - Mazda Motor Corporation (Mazda) announced today that it will gradually roll out a new version of its brand symbol, embodying its unwavering belief and enduring commitment to shaping the future. This brand symbol will also be featured at the Mazda booth at the Japan Mobility Show 2025, a place to showcase the future of the Mazda brand to the world, delivering Mazda's new brand expression to visitors.  Mazda booth at Japan Mobility Show 2025 featuring the new version of the brand symbolThe new version of Mazda’s brand symbol inherits the spirit of its symbol introduced in June 1997, representing the letter 'M' with the evocation of soaring wings. This embodies the Company’s commitment to continuous self-reform and dynamic, unceasing growth. It demonstrates the evolution of the brand toward the next generation.The sleek and bold form enhances visibility, particularly in digital environments, resulting in a more refined design. The new version of the wordmark, launched alongside it, adopts a modern style. The new version of the brand symbol and wordmark are now being adopted on the Mazda corporate website starting today.New version of the brand symbol in the digital areaThe new version of the brand symbol and the current brand symbol will be applied optimally according to location and media characteristics to enhance global brand recognition.Mazda will continue to pursue the "Joy of Driving" under its core value of “Radically Human,” and aim to deliver the "Joy of Living" by creating moving mobility experiences in the daily lives of its customers.*Definition of Each Mark Reference- Mazda corporate website featuring the new version of the brand mark:https://www.mazda.com/en/- Mazda brand mark history page:https://www.mazda.com/en/about/history/mark- Japan Mobility Show 2025 Mazda Exhibit Release:https://newsroom.mazda.com/en/publicity/release/2025/202510/251014a.html  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, October 29, 2025 - (JCN Newswire via SeaPRwire.com) - NEC Corporation (NEC; TSE: 6701) and the Cambodian Mine Action Center (CMAC, *1), the national institution responsible for landmine clearance activities in Cambodia, with assistance from JICA (*2), conducted a proof-of-concept using AI to predict landmine-contaminated areas. This initiative aims to contribute to rapid and efficient clearance operations to eliminate landmine casualties. The proof-of-concept achieved highly accurate predictions, with a match rate exceeding 90% against actual landmine locations.This initiative also received recognition through "The GICHD Innovation Award 2025," hosted by the Geneva International Centre for Humanitarian Demining (GICHD, *3), which honors outstanding technologies contributing to progress in demining activities. The award was presented at a ceremony held in Luxembourg on Tuesday, October 28. Removing landmines in an area                                   Award Ceremonypredicted by AI in Cambodia                                     ©GICHD/PANCAKE! PhotographieThe use of landmines remains a humanitarian issue worldwide, particularly hindering community and economic development for extended periods in post-conflict nations. It is estimated that approximately 100 million people face the threat of landmines, with one person losing their life to a landmine every 90 minutes (*4).In Cambodia, civil war spanning the 1970s and 1990s led to the widespread burial of landmines across the country. Despite years of dedicated clearance efforts, remnant landmines persist in some areas today. These landmines prevent the use of land for farming and residential purposes, posing serious obstacles to recovery and development.The Cambodian government, based on the Ottawa Treaty (Convention on the Prohibition of the Use, Stockpiling, Production and Transfer of Anti-Personnel Mines and on Their Destruction) signed in 1997, has set a target of completing landmine clearance within Cambodia by 2030. To achieve this, it is expected that advanced technologies such as AI will be utilized to reduce survey time.This demonstration targeted approximately 1 million square meters of Cambodia's landmine fields. NEC's AI analyzed information based on data that included CMAC's records of detected landmine locations, resident-provided information, and open data such as river/mountainous terrain locations and factory/critical building sites. It then accurately predicted areas with a high probability of containing buried landmines.Traditionally, identifying potential landmine-infested areas required extensive, unorganized data and significant manpower over long periods. By leveraging AI, this process can now be performed quickly with fewer personnel, demonstrating the potential to support swift and efficient landmine clearance.Going forward, NEC will continue striving to further improve AI's accuracy. Working with CMAC, with assistance from JICA, and strengthening collaboration with the Japanese government, NEC will accelerate efforts toward achieving Cambodia's goal of completing landmine clearance by 2030. Furthermore, NEC aims to contribute to other landmine-affected countries using this technology in the future.(*1) Cambodian Mine Action Center (CMAC)Location: Phnom Penh, Cambodia; Director: Heng Rathana(*2) Japan International Cooperation Agency(*3) Geneva International Center for Humanitarian Demining (GICHD)Location: Geneva, Switzerland; Director: Stefano Toscan(*4) Source: the-monitor.org/reports/landmine-monitorLandmine Monitor 2024 Full PaperAbout NEC CorporationNEC Corporation has established itself as a leader in the integration of IT and network technologies while promoting the brand statement of “Orchestrating a brighter world.” NEC enables businesses and communities to adapt to rapid changes taking place in both society and the market as it provides for the social values of safety, security, fairness and efficiency to promote a more sustainable world where everyone has the chance to reach their full potential. For more information, visit NEC at https://www.nec.com.  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Japan, October 29, 2025 - (JCN Newswire via SeaPRwire.com) - Honda Motor Co., Ltd. Director, President and Representative, Toshihiro Mibe today held a press conference at the Japan Mobility Show 2025.Following is an overview of his remarks, including support information:Honda exhibits mobility products and technologies for land, sea, skies and outer spaceWorld premiere of prototype of Honda 0 α, new SUV model for the Honda 0 SeriesWorld premiere of EV OUTLIER Concept, new vision for motorcycles beyond 2030World premiere of Super-ONE Prototype, compact EV will create excitement and uplifting feeling in people’s daily livesHonda exhibits sustainable rocket used for launch and landing test in June 2025About Japan Mobility Show 2025Honda is a company that has always put its heart and soul into realizing its own dreams. This year, Honda is exhibiting a wide variety of mobility products and technologies for land, sea and skies, and also for outer space. Honda would like visitors to ride and touch these items on display to feel the excitement for the future envisioned by Honda. Next-generation EVs for electrified eraHonda is working toward an ambitious goal of achieving carbon neutrality for all of its products and corporate activities by 2050. Although the market environment surrounding electrification continues to be uncertain, Honda believes that, in the long run, the shift toward EVs will continue. Therefore, Honda is steadily preparing to deliver attractive EV models in the upcoming electrified era.Honda 0 Series, next-generation EVs of Honda Honda 0 Series is the next-generation series of EVs that Honda will offer by going back to the starting point of Honda as an automaker and creating new EVs from “zero” based on original ideas. With the unique development approach of “Thin, Light, and Wise.”, Honda 0 Series will defy existing conventions that EVs are “thick and heavy” and create completely new value.   The prototype of the Honda 0 Saloon, the flagship model of Honda 0 Series, is built on a low-floor platform dedicated to EVs and features both sporty styling with a low vehicle height and a much more spacious cabin space than people would expect from the exterior design.The prototype of the Honda 0 SUV, a mid-size SUV which is the first Honda 0 Series model scheduled for market launch, features a spacious cabin with a clear and unrestricted field of view and great flexibility, realized by applying the unique “Thin, Light, and Wise.” development approach to an SUV to further increase the interior space.  Honda 0 Saloon Prototype                                 Honda 0 SUV PrototypeThese models feature ASIMO OS, the original Honda vehicle OS, which will enable continuous advancement of various functions even after the purchase of the vehicle. So, the more the customer uses it, the more personalized the car becomes to offer “ultra-personal optimization” of the customer’s mobility experience.  Honda 0 α, a new SUV for Honda 0 SeriesHonda is presenting the world premiere of the prototype of the Honda 0 α (alpha), a new SUV model for the Honda 0 Series. Featuring a sleek and sophisticated design unique to Honda 0 Series and original proportions that express the dynamic nature of SUVs, the Honda 0 α will blend beautifully with both urban and natural environments, supporting people’s lives in every situation.By applying packaging design based on the “Thin” approach, styling with a low vehicle height was achieved without compromising ground clearance, creating a thin cabin that still offers a spacious and comfortable space for occupants.Honda is planning to begin global sales of the production model of Honda 0 α, mainly in Japan and India, in 2027. With this “gateway model” to the Honda 0 Series, Honda will strive to offer new value to a greater number of customers around the world. In Japan, three Honda 0 Series models — Honda 0 Saloon, Honda 0 SUV, and Honda 0 α — will go on sale before the end of the fiscal year ending March 31, 2028. Honda 0 α PrototypeAcura RSX Prototype, a next-generation EV model for Acura brandHonda is also presenting the Japan premiere of the Acura RSX Prototype, a next-generation EV model for the Acura brand.The Acura RSX Prototype is the first model to adopt the next-generation EV platform developed independently by Honda. It also features ASIMO OS, the original Honda vehicle OS, which will enable the vehicle to learn the preferences and driving patterns of each customer and realize “ultra-personal optimization” of the mobility experience.Acura RSX Prototype *The model on display will feature a different color.EV OUTLIER Concept, a new electric motorcycle model that proposes a new vision for motorcycles beyond 2030Honda is presenting the world premiere of the EV OUTLIER Concept. Not just an extension of existing motorcycles, this concept model proposes a new vision for motorcycles beyond 2030.Taking advantage of the high degree of freedom of the layout unique to electric motorcycles, the EV OUTLIER Concept features in-wheel motors on both the front and rear wheels, achieving dynamic and low-proportion styling. Through electrification, Honda will continue to create unprecedented value with its motorcycles as well. EV OUTLIER ConceptThe “joy of driving,” the enduring philosophy of HondaWhile preparing for the upcoming electrified era, the pursuit of the “joy of driving” unique to Honda – the sense of oneness the driver feels with the vehicle – will never change regardless of the times or type of powertrain. Honda is offering a wide range of products that enable its customers to experience this “joy of driving,” whether they are EV or hybrid models.Super-ONE Prototype, a compact EV that creates excitement and an uplifting feeling in people’s daily livesHonda is presenting the world premiere of the Super-ONE Prototype, a compact EV filled with the playful mind of Honda, which will create new excitement and an uplifting feeling in people’s daily lives.Leveraging the lightweight platform advanced for N Series models, the Super-ONE Prototype realizes sporty and nimble driving. In addition, its wide stance with extended tread, realized by prominently flared blister fenders, enables a stable and dynamic driving experience.Moreover, it features “Boost Mode” developed exclusively for this model. As the power output increases, engine sound fills the cabin in sync with the feeling of shifting gears, as if driving an engine-powered vehicle. The Super-ONE offers an uplifting driving experience by combining outstanding acceleration unique to EVs and the fun of driving engine-powered vehicles.Starting in 2026, the Super-ONE will be launched first in Japan, followed by other markets with strong demand for compact EVs, such as various Asian countries and the U.K. Super-ONE PrototypePrelude, a specialty sports model embodying the unrelenting Honda sports mindsetHonda is also exhibiting the new Prelude, a specialty sports model Honda developed by fully applying an engine and technologies that Honda has perfected over many years, to carry forward the “joy of driving” into the full-fledged electrified era. The development of the new Prelude began with a strong desire to create a model that represents the Honda of today, and it was perfected as a model Honda recommends with absolute confidence.New PreludeCreating new value through enhanced application of intelligent technologiesHonda is striving to continue offering new value through a variety of mobility products and services. The key element in realizing such new value is the enhanced application of intelligent technologies. As one of the core intelligent technologies, Honda is strengthening the development of its next-generation ADAS.When the driver sets a destination on the navigation system, the ADAS will enable the vehicle to take charge of driving, such as controlling the accelerator and steering wheel, to achieve a comfortable ride to the destination. This function will give the driver peace of mind as if an experienced driver is in charge of driving operations, which will provide confidence even on unfamiliar roads and significantly reduce the burden of driving.Honda is currently testing its next-generation ADAS on public roads in the U.S., making steady progress in development. Starting around 2027, Honda will apply this technology not only to its EVs, but also to hybrid models to offer new value to the greater number of customers through their experience of expanding the freedom of mobility.  A wide variety of mobility products and technologies for land, sea, skies and outer spaceIn addition to motorcycle and automobile products and technologies, as a comprehensive mobility company, Honda has been offering a wide range of mobility products for land, sea, and skies. Including power products such as tillers and outboard motors, as well as the HondaJet, a light business jet, Honda is offering a wide variety of mobility products that will help people expand their life’s potential.Including next-generation mobility products such as micromobility vehicles that will make last-mile mobility more convenient, and eVTOLs that will make mobility in the skies more accessible for more people, Honda will continue taking on challenges to spread the “joy and freedom of mobility” to more people.And now, Honda has expanded its challenges to outer space.Outer space - Taking on a new frontier with sustainable rocketsThe actual rocket Honda used for the launch and landing test conducted in Hokkaido, Japan in June 2025 is also on display at the Honda booth. Honda is striving to develop environmentally-responsible “sustainable rockets” which will enable the reuse of the rocket as well as the use of renewable fuel.  Test being conducted in Hokkaido, Japan          Actual launch and landing test in June 2025(Photo taken in May, 2025)In the testing in June, precise control was applied on the rocket’s attitude and speed from takeoff to landing, to achieve the exact rocket behaviors planned. This success was achieved by the collective strength of Honda technologies, including control technologies amassed through automated driving and aircraft development, as well as the passion of each and every Honda associate “at the spot” who kept taking on challenges with determination.Honda rocket research and development has just taken its first step. No matter what difficulties lie ahead, Honda will overcome them by continuing to take on challenges without giving up. ClosingIn line with the Honda Global Brand Slogan — The Power of Dreams — How we move you. — each and every Honda associate with dreams and passion will continue taking on new challenges to carve out the future of Honda and create value only Honda can create.The Honda booth is introducing the future Honda aims to realize through its wide variety of mobility products and technologies, enabling visitors to feel excitement for the future. For more details, please visit: https://global.honda/en/newsroom/news/2025/c251029eng.html  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com