Singapore and Japan, September 25, 2025 - (JCN Newswire via SeaPRwire.com) - SC Ventures by Standard Chartered Bank, which builds and invests in breakthrough ventures in and beyond banking, together with Fujitsu, a leading developer of quantum software and hardware, are set to join forces on September 25 to incubate Project Quanta. The project will integrate multiple software and hardware technologies to provide clients a platform to rapidly explore, develop and integrate quantum computing and quantum-inspired applications.The joint venture will leverage Fujitsu’s expertise in quantum computing R&D and software-and-algorithm development as well as insights gained through the development of its superconducting quantum computer. It will bring this expertise together with SC Ventures’ venture building prowess and deep insights into financial institutions to accelerate the development of quantum use cases, intellectual property, resources and value.In this platform, in addition to the development environment, it provides pre-built algorithms in areas such as fraud detection, risk simulations, derivative pricing, and credit decision, enabling users to develop their own algorithms. We also provide access to data and backend hardware, allowing users to test their algorithms.This project will utilize Fujitsu’s quantum computing technology. Fujitsu has been developing quantum computing capabilities through both software and hardware advancements utilizing multiple joint research initiatives. Based on the collaboration with RIKEN, Fujitsu is currently developing a 1,000-qubit superconducting quantum computer, scheduled to begin operation in fiscal 2026.Looking ahead, the company is also planning the development of a plus-10,000 qubit (250 logical qubit) superconducting quantum computer by fiscal 2030.Apurv Suri, Client Engagement & Partnerships Lead, SC Ventures, comments:“The current quantum development industry is fragmented with some companies excelling at hardware integration while others are better at quantum algorithm building tools. By joining forces with Fujitsu, we want to unlock quantum resources and talent on one platform for corporates looking to scale their quantum capabilities.”Stafford Bond, Head of Growth Investments, Fujitsu Services Limited, comments:“At Fujitsu, we are committed to solving the world’s most complex challenges through innovation and collaboration. Partnering with SC Ventures on Project Quanta represents a bold step toward democratising access to quantum capabilities and realising true quantum advantage. By combining our expertise in quantum technologies and integration with SC Ventures’ deep industry insight and venture building pedigree, we aim to accelerate the practical application of quantum technologies and unlock transformative value for businesses.”Related LinksSC VenturesFujitsu Services Limited Fujitsu starts official development of plus-10,000 qubit superconducting quantum computer targeting completion in 2030 (August 1, 2025, Press release)About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers around the globe, our 113,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: AI, Computing, Networks, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$23 billion) for the fiscal year ended March 31, 2025 and remains the top digital services company in Japan by market share. Find out more: global.fujitsuAbout Standard CharteredWe are a leading international banking group, with a presence in 53 of the world’s most dynamic markets. Our purpose is to drive commerce and prosperity through our unique diversity, and our heritage and values are expressed in our brand promise, here for good.Standard Chartered PLC is listed on the London and Hong Kong stock exchanges. For more stories and expert opinions please visit Insights at sc.com. Follow Standard Chartered on X, LinkedIn, Instagram and Facebook. Insightssc.comXLinkedInInstagramFacebookAbout SC VenturesSC Ventures builds and invests in breakthrough ventures in and beyond banking. SC Ventures by Standard Chartered provides a platform for organisations to collaborate and co-create fintech ecosystems to reimagine the future of finance. For more information, please visit www.scventures.io and follow SC Ventures on LinkedIn.SC VenturesLinkedInPress ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiriesSC VenturesChi-an ChangPR & Communications Lead,Chian.Chang@sc.com  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, September 25, 2025 - (JCN Newswire via SeaPRwire.com) - Hitachi High-Tech Corporation ("Hitachi High-Tech"), and ELITechGroup S.p.A. (Head Office: Italy, "ELITech") have entered a Collaboration, Manufacturing and Supply Agreement (the "Agreement") in the field of molecular testing for infectious disease.Hitachi High-Tech has development and technical capabilities such as photometric analysis and automation utilized for its life sciences and in-vitro diagnostics products. ELITech offers fully automated PCR*1 testing systems and reagents for the European market, with a particular strength in reagents for a wide range of test items. Both companies have been jointly developing fully automated PCR testing system (the "System") primarily for the diagnosis and monitoring treatment of infectious diseases. This Agreement governs that Hitachi High-Tech supplies of the System to ELITech.The System offers continuous sample and reagent loading as well as random-access capabilities in accordance with the needs of the laboratory, together with fully automated functions from sample preparation to measurement. The joint development efforts will focus on creating innovative and flexible PCR platform that enhances operational efficiency in microbiology and virology laboratories, ultimately contributing to improved patient care.In Japan, Hitachi High-Tech will exhibit the System under the name “LABOSPECT GA-5” at the JACLaS EXPO 2025 in Yokohama, Japan, from October 3 through October 5, 2025.*1 Polymerase Chain Reaction (PCR): A method of amplifying very small samples of DNA fragments from cells.BackgroundIn the field of healthcare, molecular testing is used to figure out the risks of diseases and constitution and to diagnose diseases based on their genetic information. The PCR method was also used during the COVID-19 pandemic and has become more widely used. As such, there is a need to improve the efficiency of testing operations through automation and reduction of testing times for multiple test items. Hitachi High-Tech and ELITech have been jointly developing a fully automated molecular testing system that can detect viruses and bacteria at an early stage. In addition, this system utilizes the technologies of Precision System Science Co., Ltd., with whom Hitachi High-Tech has a business alliance with respect to the genetic testing business.Future DevelopmentGoing forward, Hitachi High-Tech will continue to foster innovation in the area of infectious diseases with ELITech, and through this partnership and others, we will build strong and long-term relationships with our partners. Hitachi High-Tech support offering of personalized medical care for each and every patient by “Diagnosis x Therapy x Digital,” providing Lumada solution through the installed base (Digitalized Assets) and domain knowledge. We aim to “make patient smile with frontline healthcare workers” and “create a society without fear of cancer” for realizing a harmonized society where environment, wellbeing and economic growth are in balance.About Hitachi High-TechHitachi High-Tech provides cutting-edge technologies, products and services to society and customers with its corporate vision of "Changing the World and Future with the Power of Knowledge" to contribute to a sustainable global environment, healthy, safe and secure lives, and the sustained development of science and industry. We manufacture and sell clinical analyzers, biotechnology products and radiation therapy systems in the healthcare field, semiconductor manufacturing and inspection equipment in the semiconductor field, as well as analytical systems and electron microscopes used in environmental fields and materials research. We are also engaged in a wide range of business areas globally, providing high added-value solutions in battery, communication infrastructure, railway inspection, digital and other industrial and social infrastructure fields. By deeply understanding the issues facing society and our customers, and utilizing the installed base (Digitalized Assets) and domain knowledge, we provide digital service through Lumada 3.0, enhanced by AI. Along with the Inspire 2027, Hitachi Group's New Management plan, we contribute to realize a harmonized society where the environment, wellbeing, and economic growth coexist in harmony. The company's consolidated revenues for FY2024 were approx. JPY 756.5 billion. For further information, visit https://www.hitachi-hightech.com/global/en/About ELITechELITechGroup is a global leader in in-vitro diagnostics, serving hospitals and diagnostic laboratories in over 100 countries through a direct sales network and trusted distribution partners. The company develops, manufactures, and markets a comprehensive range of diagnostic products and solutions, including instruments, reagents, and software. With a global team of about 600 professionals, ELITechGroup is proud to be a part of Bruker Corporation. Alongside Bruker's other businesses in the Bruker Microbiology & Infection Diagnostics division (BMID), ELITechGroup remains deeply committed to fully meeting the evolving needs of its customers. The company continues to develop state-of-the-art technologies and innovative solutions that address the challenges faced by today's–and tomorrow's–laboratories. For more information, visit the ELITech website (https://www.elitechgroup.com/).Business ContactMolecular Systems Marketing Dept.,Sales & Marketing Div.,Diagnostic System Business,Healthcare Business Group,Hitachi High-Tech Corporation Contact form  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, September 25, 2025 - (JCN Newswire via SeaPRwire.com) - JERA Co., Inc. (“JERA”) and DENSO CORPORATION (“DENSO”) hereby announce that they have today begun demonstration testing of hydrogen production at JERA’s Shin-Nagoya Thermal Power Station (Nagoya, Aichi) using SOEC*1 water electrolysis systems developed by DENSO (electrolysis power*2: 200kW).Because it emits no CO2 when burned, hydrogen is being considered for use in a variety of applications including power generation, transportation, and industry and is expected to play a key role in achieving a carbon-neutral society. In this context, in August 2024 JERA and DENSO began jointly developing high-efficiency hydrogen generation technology using SOECs developed by DENSO*3 and have since moved forward with preparations for hydrogen production demonstration testing. The two companies have now begun Japan’s first demonstration testing at a thermal power station. This demonstration testing aims to achieve hydrogen production with the world’s highest-level electrolysis efficiency by applying DENSO’s heat-management technology to minimize the heat discharged by the SOECs. Going forward, based on the results of the demonstration testing, we aim to scale up the electrolysis power from 200kW to several thousand kW as we accelerate efforts to drive the practical application of SOEC next-generation fuel production systems.Aiming to achieve net-zero CO2 emissions from its domestic and international operations by 2050, JERA is building a hydrogen and ammonia supply chain and pursuing the development of zero-emissions thermal that emits no CO2 during power generation. DENSO is applying technologies it has nurtured in the mobility field to further advance development aimed at hydrogen utilization. Through this joint demonstration testing, both companies will work for the early establishment of a global supply chain for green hydrogen and ammonia and contribute to finding solutions for global decarbonization and energy issues.*1 SOEC (Solid Oxide Electrolysis Cell): A system that operates at high temperatures using a ceramic membrane as an electrolyte to electrolyze steam and produce hydrogen. SOECs have exceptionally high electrolysis efficiency (up to around 80%) and offer the advantage of using less electricity than other water electrolysis methods such as PEM and alkaline.*2 Electrolysis Power: Electric power allocated to water electrolysis.*3 See 5 August 2024 press release: DENSO and JERA to Jointly Develop High-Efficiency Hydrogen Generation Technology that Combines SOEC with Waste Heat Utilization and to Conduct Joint Demonstration Testing at a JERA Thermal Power StationView of the Hydrogen Production Demonstration Testing Facilities Installed at JERA Shin-Nagoya Thermal Power Station  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

Santa Clara, Münster, September 23rd, Tokyo 24th 2025, - (JCN Newswire via SeaPRwire.com) - Hitachi, Ltd. (TSE:6501, "Hitachi") is advancing the realization of a “Harmonized Society” where environment, wellbeing, and economic growth coexist in balance. As One Hitachi, the company is strengthening its portfolio to harness domain expertise and accelerate AI-driven innovations that transform social infrastructure. The Hitachi Group has agreed to acquire synvert, a company headquartered in Germany, as a wholly owned subsidiary of its U.S. subsidiary GlobalLogic Inc. (“GlobalLogic”)from Maxburg, a leading private equity fund focusing on founder-led technology companies inthe German-speaking region. This acquisition aims to accelerate the deployment of HMAX, Hitachi’s solution suite advancing operational autonomy and business model innovation through Agentic and Physical AI, solving customer and societal challenges in the AI era.synvert is a leading consulting firm in the data and AI space, delivering advanced expertise in AI-driven business design, data access and governance, integration, and operations. With a portfolio of over 200 clients, synvert helps enterprises unlock value and drive intelligent, data-powered transformation. synvert maintains advanced partnerships with leading cloud and data platform vendors, including Databricks and Snowflake, alongside major public cloud vendors(AWS, Microsoft Azure, Google Cloud).Once the acquisition is completed, synvert will complement GlobalLogic’s deep capabilities in AI and digital engineering, while adding end-to-end strength across the enterprise data value chain and accelerating the development of Agentic and Physical AI. synvert’s strong presence in Germany, Switzerland, Spain, Portugal, and the Middle East will help expand markets for HMAX through collaboration with Hitachi Rail and Hitachi Energy. The acquisition is expected to close in the fiscal year ending March 2026 (April 1, 2025 to March 31, 2026), subject to regulatory approval.Advancing Hitachi’s AI Vision Led by the Digital Systems & Services Sector Hitachi’s Digital Systems & Services sector, leading the company’s AI strategy under Lumada 3.0, is driving the evolution from Generative AI to Agentic AI—which autonomously coordinates multiple tools to perform complex tasks—and now to Physical AI, where intelligent systems interact with and control the physical world through robotics and IoT-enabled devices.The Hitachi AI Center of Excellence (AI CoE) has led the development and deployment of over 1,000 generative AI use cases, including mission-critical applications. Agentic AI is actively in use across executive, engineering, and frontline layers to enhance risk analysis, predictive maintenance, and system integrator efficiency, with over 200 global operational implementations.Relevance of the synvert AcquisitionCustomers gain immediate advantages from a platform-first architecture and industrialized MLOps, resulting in faster AI time-to-value, responsible scaling with built-in AI guardrails, and the ability to add managed services that improve resilience and reduce total cost of ownershipAs Agentic AI evolves to orchestrate intelligent decision-making and task execution across vast, dynamic datasets, a modern, enterprise-grade data foundation becomes mission-critical. synvert brings over 550 highly skilled specialists in data governance, data platform engineering, and advanced analytics—with deep expertise in data warehouse and lakehouse architectures. Their capabilities enable the seamless ingestion, management, and activation of data needed to power autonomous agents and real-time decision systems.By integrating synvert’s proven data and AI consulting strengths with GlobalLogic’s VelocityAI platform and digital engineering leadership, we extend our end-to-end value across the enterprise data lifecycle—positioning Hitachi to deliver scalable, secure, and production-ready Agentic and Physical AI solutions across industries.Comment from Jun Abe, Executive Vice President of Hitachi, Ltd., General Manager of the Digital Systems & Services Division“Hitachi is accelerating social innovation by addressing urgent societal challenges—such as labor shortages and knowledge transfer among frontline workers in transportation, energy, gas,and railway sectors—through the advancement of its own AI-driven transformation and the delivery of its outcomes to customers. By integrating synvert’s outstanding data analytics and consulting capabilities with GlobalLogic’s digital engineering expertise, we will enhance competitiveness through Agentic AI and accelerate HMAX deployment. We aim to deliver digital value to all and realize a safe, secure, and sustainable Harmonized Society.”Comment from Srini Shankar, President and CEO, GlobalLogic“Integrating synvert into GlobalLogic will play a key role in accelerating our global strategy. It will strengthen our data and consulting capabilities and expand our presence in Europe and the Middle East across industries like energy, retail, financial services, and insurance. Once the acquisition is completed, we expect to rapidly deliver innovation through end-to-end development of data-driven AI services, and accelerate efforts in Agentic and Physical AI.”Comment from André Holhozinskyj, CEO, synvert“Joining the Hitachi Group, which has strengths in OT and products, is an ideal step in synvert’s growth story. GlobalLogic’s capabilities and regional strategy align well with synvert, and we believe this partnership will drive further growth. synvert’s identity resonates with Hitachi’s purpose-driven culture, and we look forward to what we can achieve together.”Company OverviewCompany Name: synvertHeadquarter and Office:Headquarter: Münster, GermanyOffices: Europe, U.S., and Middle EastBusiness: Provides sustainable data value chains from strategy to analytics platform operations; over 3,000 projects across finance, manufacturing, insurance, public sector, and energyEmployees: Over 550 (as of June 2025)Founded: 1991Website: https://synvert.com/en-en/CEO: André Holhozinskyj (CEO)As a private equity fund focusing on founder-led technology companies, Maxburg’s successful partnership with synvert concludes with a strategic transaction with the Hitachi Group. Over the past five years, synvert has grown into one of the leading data and AI service providers in EMEA, increasing sales and profitability by a factor of eight through disciplined execution and strong leadership. The terms of the acquisition are not disclosed.About Hitachi, Ltd.Through its Social Innovation Business (SIB) that brings together IT, OT(Operational Technology) and products, Hitachi contributes to a harmonized society where the environment, wellbeing, and economic growth are in balance. Hitachi operates globally in four sectors – Digital Systems & Services, Energy, Mobility, and Connective Industries –and the Strategic SIB Business Unit for new growth businesses. With Lumada at its core, Hitachi generates value from integrating data, technology and domain knowledge to solve customer and social challenges. Revenues for FY2024(ended March 31, 2025) totaled 9,783.3 billion yen, with 618 consolidated subsidiaries and approximately 280,000 employees worldwide. Visit us at www.hitachi.com.About GlobalLogicGlobalLogic (www.globallogic.com) is a leading digital engineering partner that helps the world's most forward thinking companies design and build innovative, AI-powered products, platforms, and digital experiences. Since 2000, we've been at the forefront of the digital revolution, now accelerating clients' transitions into tomorrow's AI-driven businesses by integrating experience design, complex engineering, AI, and data expertise. Headquartered in Silicon Valley, GlobalLogic is a Hitachi Group Company operating under Hitachi, Ltd. (TSE: 6501), which contributes to a sustainable society with a higher quality of life by driving innovation through AI and technology as the Social Innovation Business. Visit us at www.globallogic.com.About MaxburgMaxburg is a Munich-based private equity fund with capital commitments of more than €1bn. Maxburg is a growth investor, supporting exceptional businesses built and led by strong founders. Maxburg focusses on technology and software, business services and consumable products (B2B and B2C) sectors in the GSA region. synvert is Maxburg’s fifth exit in the technology sector after having successfully invested in Maltego, KGS, Starface and Tenado. For more information about Maxburg visit maxburg.com/en/  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO, Sept 25, 2025 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Electric Building Solutions Corporation (MEBS, Head Office: Chiyoda-Ku, Tokyo; President: Iwao Oda) today announced the introduction of KEGMIL, a cloud-based platform developed by the Singapore-based startup FTV LABS PTE. LTD. (FTV LABS) to improve the management of field services for elevator and escalator maintenance in overseas markets. KEGMIL will be launched in Singapore in October 2025, with the aim of expanding its deployment primarily across Southeast Asia and eventually to other regions.In today’s world, maintenance services for elevators and escalators have become increasingly important as a means of ensuring user safety and meeting the growing demands for convenience and comfort. At the same time, workforce aging and inefficient work processes are emerging as major issues. Introducing KEGMIL into elevator maintenance field services will allow MEBS to improve efficiency by allowing everything from work instructions and progress confirmation to rapid dispatch of maintenance workers be completed through the KEGMIL app. Specifically, during our pre-introduction verification, we obtained confirmation that the amounts of work involved in creating maintenance worker assignment plans and maintenance worker work reports could be reduced by approximately 90% and 50%, respectively.In the future, together with M’s BRIDGE, which enables remote monitoring and inspection, MEBS will enhance the efficiency of its comprehensive maintenance services and promote the provision of consistent and high-quality field services.Main Features of the KEGMIL System1) Improves work quality and efficiency through clarification of work items and content.Work procedures for each product can be standardized using the workflow and checklist creation functions. Task-specific clarification ensures consistent work quality.Work efficiency is enhanced by centrally managing the necessary procedures, inspection items, and other related materials for each operation and making them available via a mobile app.Work instructions can be configured not only for each product, but also for each site and unit according to their respective specifications, enabling detailed work guidance.2) Efficient maintenance worker allocation and precise work orders minimize downtime and enable rapid recovery.Monitoring the progress of workers’ tasks periodically and combining this with GPS location data facilitates rapid dispatching of workers in response to emergencies such as equipment failures.The use of checklists makes it possible to provide precise work instructions according to the elevator's condition and facilitates early recovery.3) Digitizing work completion reports and signatures on mobile devices streamlines manual work allows the system to be used for emergency response work.Centralized management of work orders, work checklists, and work reports on mobile devices facilitates the automatic generation of electronic reports—complete with signatures—in the designated format upon the completion of each work assignment, eliminating the need to return to the office between assignments.Attaching photos and videos to reports allows work to be executed accurately even by personnel not directly responsible for the unit in question during emergencies.BackgroundElevators and escalators, which support mobility worldwide as part of the social infrastructure, are subject to increasing demands with each passing year with regard to user safety, convenience, and comfort. Consequently, the importance of providing maintenance services that satisfy these demands is also growing. Meanwhile, many countries around the world are facing the same challenge as Japan of securing a sustainable workforce as the working population continues to age, and in addition to securing human resources, improving maintenance efficiency and proceeding with DX have become urgent priorities.However, in the field service sector for elevators and elevators, much of the recordkeeping and management still relies on paper and manual processes, and much of the data acquired in the field has to be manually input into multiple systems at the office, which results in all kinds of inefficient business processes.The introduction of the KEGMIL platform into our elevator and escalator maintenance field services makes it possible to complete a wide range of procedures entirely on the app, including clear work instructions using checklists and photographs, real-time progress confirmation of various work tasks, emergency dispatch of maintenance workers using GPS location data, and digital signatures.Together with the digital transformation (DX) of our maintenance operations, we will continue to develop our global remote-maintenance service M's BRIDGE, which enables continuous monitoring, inspection, and data analysis of elevators. This will enhance the overall efficiency of our maintenance services and achieve uniform and high-quality field services.About KEGMILKEGMIL* is a cloud-based Field Service Management platform provided by FTV LABS that promotes operational efficiency through the digitization of on-site work in mechanical & electrical engineering sector, as well as specialized fields such as medical equipment servicing. By digitizing business records, work reports, schedule management, and other tasks that were previously scattered across paper media and multiple software applications and centralizing their management within the KEGMIL app, these operations can be performed more smoothly and efficiently. In addition, by making it possible to instantly verify consistent work processes on mobile devices at the worksite—including the preparation of work procedures, items, and checklists, as well as viewing related documents such as drawings—KEGMIL reduces manual work time and labor while simultaneously achieving uniform work quality.Future DevelopmentBy centralizing maintenance service information that was previously managed on paper or across disparate systems, KEGMIL will make use of field data accumulated through AI, machine learning, IoT, and IoE to optimize the allocation of maintenance workers, which is currently handled independently in each region, and to globally standardize recovery work operations. Through this, MEBS is aiming to provide consistent and even higher quality field services and realize advanced operations in the global market.M's BRIDGE is a registered trademark of Mitsubishi Electric Corporation, except in certain regions.* URL: https://kegmil.com/About Mitsubishi Electric Building Solutions CorporationMitsubishi Electric Building Solutions Corporation is a consolidated subsidiary of Mitsubishi Electric Corporation established in April 2022 that conducts a comprehensive range of operations in the building systems business, from development and manufacturing to maintenance and renewal. As a building solutions provider, we support the economic and social infrastructure through one-stop integrated solutions that combine a wide range of building-related products and services, including elevators, escalators, air conditioning and refrigeration equipment, and building systems, as well as with our extensive experience in building operation and management, and advanced digital technology. From buildings to building complexes and even entire cities, we contribute to enriching human life in buildings and urban spaces by solving a wide variety of issues that are closely linked to people and society, with the ultimate aim of realizing smart cities. For more information, please visit www.mebs.com/ Customer InquiriesCorporate Planning Department, Global Business GroupMitsubishi Electric Building Solutions Corporationbod.inquiry@rk.MitsubishiElectric.co.jp Media InquiriesCorporate Communication DivisionMitsubishi Electric Building Solutions Corporationa_mebs_press@meltec.co.jp Press Release: https://www.acnnewswire.com/docs/files/2025925.pdf  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com

TOKYO and CAMBRIDGE, Mass., Sept. 24, 2025 - (JCN Newswire via SeaPRwire.com) - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, “Eisai”) and Biogen Inc. (Nasdaq: BIIB, Corporate headquarters: Cambridge, Massachusetts, CEO: Christopher A. Viehbacher, “Biogen”) announced today that the Therapeutic Goods Administration (TGA)of Australia has approved the humanized anti-soluble aggregated amyloid-beta (Aβ) monoclonal antibody “LEQEMBI®” (brand name, generic name: lecanemab) for mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease (AD) (collectively referred to as early AD) in adults who are either ApoEε4* non-carriers or heterozygous carriers.In response to February 2025 TGA decision not to approve lecanemab as a treatment for people with early AD, in March 2025, Eisai requested a review by the Administrative Review Tribunal. As a result of discussions during this process, the TGA and Eisai reached an agreement that led to the approval of LEQEMBI. In Australia, the number of people living with dementia was estimated to be approximately 425,000 in 2024, and is reported to increase to nearly 1,100,000 by 2065.1 AD is considered the most common cause of dementia, typically accounting for 60-70% of cases.2 AD is a progressive, relentless disease with amyloid beta (Aβ) and tau as hallmarks that is caused by a continuous underlying neurotoxic process that begins before amyloid plaque removal and continues afterward.3,4,5 Only LEQEMBI fights AD in two ways– targeting both the toxic protofibrils** and amyloid plaque 2, which can impact tau downstream. Eisai serves as the lead for lecanemab’s development and regulatory submissions globally with Eisai and Biogen co-commercializing and co-promoting the product and Eisai having final decision-making authority.* Apolipoprotein E is a protein involved in the metabolism of fats in humans. It is implicated in AD. People with only one (heterozygous) or no copy (non-carriers) of the ApoE ε4 gene are less likely to experience ARIA than people with two ApoE ε4 copies (homozygous).2 ARIA is a recognized important side effect with lecanemab that involves swelling and potential bleeding in the brain.6,7** Protofibrils are believed to contribute to the brain injury that occurs with AD and are considered to be the most toxic form of Aβ, having a primary role in the cognitive decline associated with this progressive, debilitating condition.3 Protofibrils cause injury to neurons in the brain, which in turn, can negatively impact cognitive function via multiple mechanisms, not only increasing the development of insoluble Aβ plaques but also increasing direct damage to brain cell membranes and the connections that transmit signals between nerve cells or nerve cells and other cells. It is believed the reduction of protofibrils may prevent the progression of AD by reducing damage to neurons in the brain and cognitive dysfunction.4MEDIA CONTACTSEisai Co., Ltd.Public Relations Department+81 (0)3-3817-5120Eisai Europe, Ltd.(UK, Europe, Australia, New Zealand and Russia)EMEA Communications Department+44 (0) 7739 600678EMEA-comms@eisai.netEisai Inc. (U.S.)Libby Holman+ 1-201-753-1945Libby_Holman@eisai.comBiogen Inc.Madeleine Shin+ 1-781-464-3260public.affairs@biogen.comINVESTOR CONTACTSEisai Co., Ltd.Investor Relations Department+81 (0) 3-3817-5122Biogen Inc.Tim Power+ 1-781-464-2442IR@biogen.com For more details, please visit: https://www.eisai.com/news/2025/pdf/enews202566pdf.pdf  Copyright 2025 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com